model-based analysis of tiling-array (mat) software Search Results


microarray cel files  (Thermo Fisher)
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Thermo Fisher microarray cel files
Overlap between GW7647-induced PPARα binding and GW7647-induced changes in expression. ( A ) Significant induction of PPARα targets by GW7647 treatment. ( B ) Number of genes significantly altered upon GW7647 treatment as determined by <t>microarray</t> analysis using criteria: fold change >1.2 and q -value <0.05. ( C ) Overlap between genes assigned to GW7647-induced PPARα binding regions and genes altered after treatment with GW7647 as determined by transcriptomics. ( D ) Percentage of GW7647-induced PPARα binding regions linked to either up- or down-regulated genes that contain at least one V$PERO site, as determined using Genomatix. Similar analysis was done for all GW7647-induced PPARα binding regions as well as a control set of promoter regions in the Genomatix promoter database with similar size range as the binding regions identified by ChIP-chip (1000–1500 bp).
Microarray Cel Files, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Overlap between GW7647-induced PPARα binding and GW7647-induced changes in expression. ( A ) Significant induction of PPARα targets by GW7647 treatment. ( B ) Number of genes significantly altered upon GW7647 treatment as determined by microarray analysis using criteria: fold change >1.2 and q -value <0.05. ( C ) Overlap between genes assigned to GW7647-induced PPARα binding regions and genes altered after treatment with GW7647 as determined by transcriptomics. ( D ) Percentage of GW7647-induced PPARα binding regions linked to either up- or down-regulated genes that contain at least one V$PERO site, as determined using Genomatix. Similar analysis was done for all GW7647-induced PPARα binding regions as well as a control set of promoter regions in the Genomatix promoter database with similar size range as the binding regions identified by ChIP-chip (1000–1500 bp).

Journal: Nucleic Acids Research

Article Title: Profiling of promoter occupancy by PPARα in human hepatoma cells via ChIP-chip analysis

doi: 10.1093/nar/gkq012

Figure Lengend Snippet: Overlap between GW7647-induced PPARα binding and GW7647-induced changes in expression. ( A ) Significant induction of PPARα targets by GW7647 treatment. ( B ) Number of genes significantly altered upon GW7647 treatment as determined by microarray analysis using criteria: fold change >1.2 and q -value <0.05. ( C ) Overlap between genes assigned to GW7647-induced PPARα binding regions and genes altered after treatment with GW7647 as determined by transcriptomics. ( D ) Percentage of GW7647-induced PPARα binding regions linked to either up- or down-regulated genes that contain at least one V$PERO site, as determined using Genomatix. Similar analysis was done for all GW7647-induced PPARα binding regions as well as a control set of promoter regions in the Genomatix promoter database with similar size range as the binding regions identified by ChIP-chip (1000–1500 bp).

Article Snippet: Affymetrix microarray CEL files were acquired and normalized using the Model-based analysis of tiling-arrays (MAT) algorithm ( ).

Techniques: Binding Assay, Expressing, Microarray, ChIP-chip